There are many methods of determining what processes occur in cells and, with one of the most flexible being fluorescence imaging. Imaging allows data to be placed in better context than many other methods, as it allows for the localisation of signals, while fluorescence allows the gathering of data on many parameters, via its intensity, wavelength, lifetime and polarisation properties. My research is aimed at developing instrumentation to allow for higher speed and lower bleaching fluorescence lifetime imaging (primarily via TCSPC), and to apply this to the examination of signalling events at the immune synapse.